Sam Simmonds and Jack van Bortvliet at the start for the hosts
Manu Tuilagi comes off the bench with Leicester City's Jay Porter on the outside.
Wing Jonny May will start in place of Joe Cokanasiga just 22 days after he dislocated his elbow in the line of club duty.
Hooker Jimmy George, who has recovered from a foot injury that kept him out of the entire fall, is included on the bench. substitutes.
A short transverse gray line
England: Steward. Noel, Porter, Farrell (Captain), watered; Smith, Van Portvleet; Genge, Kwan Dickie, Sinclair, Ribans, Hill, Etogi, Curry, Symonds.
Subs: George, MVunipola, Hayes, Coles, PVunipola, Youngs, Slade, Tuilagi.
Symonds returns to the starting lineup
Symonds, who missed Australia's summer tour with a thigh problem, will start for England for the first time since the Six Nations defeat. In France in March.
There will be a boon for him to take over the ball-carrying duties as
Billy Vunipola and Coles have been let go who have gained the most meters of any striker. England vs Pumas on the benchVan Poortvliet was rewarded for his daring cameo in the second half against Argentina which included a try in Within 30 seconds from his submission.
The now 27-year-old Raybans moved to Northampton from Western District in 2017 and is brought into England through his grandfather, who settled in C. Nubian Africans after emigrating from London.